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Alkylsulfanyl-1,2,4-triazoles, a New Class of Allosteric Valosine Containing Protein Inhibitors. Synthesis and Structure–Activity Relationships

✍ Scribed by Polucci, Paolo; Magnaghi, Paola; Angiolini, Mauro; Asa, Daniela; Avanzi, Nilla; Badari, Alessandra; Bertrand, Jay; Casale, Elena; Cauteruccio, Silvia; Cirla, Alessandra; Cozzi, Liviana; Galvani, Arturo; Jackson, Peter K.; Liu, Yichin; Magnuson, Steven; Malgesini, Beatrice; Nuvoloni, Stefano; Orrenius, Christian; Sirtori, Federico Riccardi; Riceputi, Laura; Rizzi, Simona; Trucchi, Beatrice; O’Brien, Tom; Isacchi, Antonella; Donati, Daniele; D’Alessio, Roberto


Book ID
118213550
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
468 KB
Volume
56
Category
Article
ISSN
0022-2623

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✍ Jian-Bing Liu; Wei-Feng Tao; Hong Dai; Zhong Jin; Jian-Xin Fang 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 169 KB 👁 1 views

## Abstract Fourteen new 1__H__‐1,2,4‐triazole derivatives containing pyridine moiety were synthesized by condensation of 1‐(pyridine‐3‐yl)‐2‐(1__H__‐1,2,4‐triazol‐1‐yl)ethanone with aryl aldehydes, and their reaction conditions were studied. The title compounds were screened for their antibacteria