The oxidation state of the cysteine residue at the active site of human protein tyrosine phosphatase (PTP-1B) greatly affects its enzymatic activity. We wished to examine peroxide-treated preparations for modifications of this enzyme with electrospray mass spectrometry in order to determine the loca
β¦ LIBER β¦
Alkylation of Escherichia coli Thioredoxin by S-(2-Chloroethyl)glutathione and Identification of the Adduct on the Active Site Cysteine-32 by Mass Spectrometry
β Scribed by Erve, John C. L.; Barofsky, Elisabeth; Barofsky, Douglas F.; Deinzer, Max L.; Reed, Donald J.
- Book ID
- 126231994
- Publisher
- American Chemical Society
- Year
- 1995
- Tongue
- English
- Weight
- 992 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0893-228X
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