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Alkylation of enolates by 3-methyl-4-chloro-4,5,6,7-tetrahydrobenz[1,2-d]isoxazole

✍ Scribed by V. A. Khripach; G. V. Ivanova


Publisher
Springer US
Year
1990
Tongue
English
Weight
393 KB
Volume
26
Category
Article
ISSN
0009-3122

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The title compound, C 18 H 20 ClNO 2 , has been synthesized by the reaction of 4-chlorobenzaldehyde, Meldrum's acid, dimedone and CH 3 NH 3 Cl(NaOAc) in ethanol under microwave irradiation. The pyridone ring adopts a screw-boat conformation and the cyclohexenone ring an envelope conformation.