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Alkylation of 2-pyridinones: Synthesis of novel acyclonucleosides

✍ Scribed by Farag A. El-Essawy; Ahmed F. Khattab

Publisher
Journal of Heterocyclic Chemistry
Year
2004
Tongue
English
Weight
227 KB
Volume
41
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

This paper presents the synthesis of some novel acyclonucleosides containing 2‐pyridinones and 2‐hydroxyethoxymethyl, 2,3‐dihydroxy‐propyl side chain. The tosylate of these nucleosides analogues could be modified to azido derivatives. Also, acyclonucleosides with 1‐ethoxymethyl, 1‐benzyloxymethyl, 1‐methylthiomethy 1 and 2‐hydroxyethyl side chains have been investigated. The O‐alkylated pyridine derivatives were obtained during most reactions.

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Synthesis of novel acyclonucleosides con
Synthesis of novel acyclonucleosides containing pyridazine
✍ Jung-Won Park; Deok-Heon Kweon; Young-Jin Kang; Woo Song Lee; Su-Dong Cho; Yong- 📂 Article 📅 2000 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 442 KB

## Abstract This paper presents the synthesis of some novel acyclonucleosides involving pyrrolo[2,3‐__c__]pyridazine and 4‐hydroxybutyl side chain.