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Alkylating agents: Studies on mechanisms of resistance in different cell lines

✍ Scribed by Institoris, E.; Bence, J.; Szikla, K.


Book ID
122586121
Publisher
Elsevier Science
Year
1987
Weight
127 KB
Volume
23
Category
Article
ISSN
0277-5379

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Survival curves and dose escalation studies of four representative human tumor cell lines exposed to the various alkylating agents are presented. With HN2, at a level of one log of cell kill there was a fivefold range in drug concentration required to achieve this degree of cell kill among the cell