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Alkylated Trihydroxyacetophenone as a MALDI Matrix for Hydrophobic Peptides

✍ Scribed by Fukuyama, Yuko; Nakajima, Chihiro; Furuichi, Keiko; Taniguchi, Kenichi; Kawabata, Shin-ichirou; Izumi, Shunsuke; Tanaka, Koichi


Book ID
127085097
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
584 KB
Volume
85
Category
Article
ISSN
0003-2700

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✍ M.J.Biscoglio de Jimenez Bonino; J.G. Fukushima; O. Cascone πŸ“‚ Article πŸ“… 1986 πŸ› Elsevier Science 🌐 English βš– 288 KB

A methodology is described for purification of histidyl peptides based on the changes in hydrophobicity induced by the specific and reversible modification of histidine residues by ethoxyformic anhydride. The mixture of modified peptides is subjected to HPLC; peptides containing modified histidines