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Alkylated purines in the DNA of various rat tissues after administration of 1,2-dimethylhydrazine

โœ Scribed by Alexie J. Likhachev; Geoffrey P. Margison; Ruggero Montesano

Book ID
113135703
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
287 KB
Volume
18
Category
Article
ISSN
0009-2797

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Induction of renal tumours in rats by th
Induction of renal tumours in rats by the administration of 1,2 dimethylhydrazine
โœ Dr. J. P. Sunter; P. V. Senior ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 662 KB

## Abstract Administration of dimethylhydrazine (DMH) to adult rats by two subcutaneous injections each of 120 mg(base)/kg body weight and spaced 10 days apart resulted in the development of renal tumours in over 90 per cent. of treated animals at 30 weeks after injection. The tumours were frequent