Alkyl group transfer from cobalt to mercury: the reaction of alkylcobalamins, alkylcobaloximes and of related compounds with mercuric acetate
✍ Scribed by G.N. Schrauzer; James H. Weber; T.M. Beckham; R.K.Y. Ho
- Book ID
- 104247346
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- French
- Weight
- 161 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Mercuric salts have been shown to inhibit the corrin dependent biosynthesis of methane by Methanobacillus omelianskii (I), presumably by reacting with the methylated corrin cofactor prior to its reductive demethylation. Nonenzymatically the reaction of alkylcobalamins with mercuric salts was reported to yield mercury dialkyls if conducted in the presence of metallic zinc as the reducing agent (I). However, Hill etg. (21, subse quently observed that the cleavage of the Co-C bond in alkylcobalamins by mercuric salts occurs by electrophilic attack and does not require reducing conditions. The reaction is believed to yield organomercurials as principal products since the ion CH3-Hg+ was detected by mass spectroscopy among the products of the reaction of methylcobalamin with mercuric acetate.