𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Alkyl (E,Z)-2-(2-benzoyl-2-ethoxycarbonyl-1-ethenyl)amino-3-dimethylaminopropenoates in the synthesis of fused pyrimidinones. A facile route to 3-aminoazino-4H-pyrimidin-4-ones

✍ Scribed by Sonja Strah; Amalija Golobič; Ljubo Golič; Branko Stanovnik

Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
580 KB
Volume
34
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Alkyl (E,Z)‐2‐(2‐benzoyl‐2‐ethoxycarbonyl‐1‐ethenyl)amino‐3‐dimethylaminopropenoates 1a,b react with het‐eroarylamines 2 to give alkyl 2‐(2‐benzoyl‐2‐ethoxycarbonyl‐1‐ethenyl)amino‐3‐heteroarylaminopropenoates 3‐13. These were cyclized into fused 3‐(2‐benzoyl‐2‐ethoxycarbonyl‐1‐ethenyl)amino‐4__H__‐azolo‐ (or azino)‐pyrim‐idin‐4‐ones 14‐18. 2‐Benzoyl‐2‐ethoxycarbonyl‐1‐ethenyl group can be easily removed from 3‐(2‐benzoyl‐2‐ethoxycarbonyl‐1‐emenyl)amino‐8‐memyl‐4__H__‐pyrido[1,2‐a]pyrimidin‐4‐one (14) to give 3‐amino‐8‐methyl‐4__H__‐pyrido[1,2‐a]pyrimidin‐4‐one (19). The structure of 1a was confirmed by X‐ray analysis.

📜 SIMILAR VOLUMES

ChemInform Abstract: Alkyl (E,Z)-2-(2-Be
ChemInform Abstract: Alkyl (E,Z)-2-(2-Benzoyl-2-ethoxycarbonyl-1-ethenyl) amino-3-dimethylaminopropenoates in the Synthesis of Fused Pyrimidinones. A Facile Route to 3-Aminoazino-4H-pyrimidin-4-ones.
✍ S. STRAH; A. GOLOBIC; L. GOLIC; B. STANOVNIK 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Reactions of alkyl (z)-2-[(E)-2-ethoxyca
Reactions of alkyl (z)-2-[(E)-2-ethoxycarbonyl-2-(2-pyridinyl)-ethenyl]amino-3-dimethylaminopropenoates with C- and N-nucleophiles. the synthesis of fused pyranones, pyridinones and pyrimidinones
✍ Lucija Jukić; Jurij Svete; Branko Stanovnik 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 84 KB

## Abstract Alkyl 2‐[2‐ethoxycarbonyl‐2‐(2‐pyridinyl)ethenyl]amino‐3‐dimethylaminopropenoates **3** and **4** were transformed with __C__‐and __N__‐nucleophiles into β‐heteroaryl‐α,β‐didehydro‐α‐amino acid derivatives **13**‐**16**, substituted 3‐amino‐4__H__‐quinolizin‐4‐one 17, 2__H__,5__H__‐benz