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Alkenyl sulphoxides as precursors to cyclopentenones and prostanoid β-side chains

✍ Scribed by Peter J. Brown; D.Neville Jones; M.Akram Khan; Nicholas A. Meanwell

Book ID: 104216931
Publisher: Elsevier Science
Year: 1983
Tongue: French
Weight: 235 KB
Volume: 24
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)81420-3

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✦ Synopsis

Conjugate additions of enolate anions to a,B-unsaturated sulphoxides follcwed by sulphoxide-ketone transformations provided simple syntheses of cyclopentenones, and 2-phenylsulphinyloct-I-en-3-one provided a convenient electrophilic prostanoid B-side chain precursor.

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