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AlkB dioxygenase in preventing MMS-induced mutagenesis in Escherichia coli: Effect of Pol V and AlkA proteins

✍ Scribed by Jadwiga Nieminuszczy; Anna Sikora; Michał Wrzesiński; Celina Janion; Elżbieta Grzesiuk


Book ID
116410500
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
142 KB
Volume
5
Category
Article
ISSN
1568-7864

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The E. coli dnaQ gene encodes the epsilon subunit of DNA polymerase III (pol III) responsible for the proofreading activity of this polymerase. The mutD5 mutant of dnaQ chronically expresses the SOS response and exhibits a mutator phenotype. In this study we have constructed a set of E. coli AB1157