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Alkalinisation of bupivacaine for sciatic nerve blockade

โœ Scribed by D. M. COVENTRY; J. G. TODD


Book ID
108622302
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
368 KB
Volume
44
Category
Article
ISSN
0003-2409

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Effect of excipient composition on the b
โœ Colombo, Gaia ;Langer, Robert ;Kohane, Daniel S. ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 531 KB

## Abstract Microparticulate formulations are often used for experimental prolongation of nerve blockade. Here we examine the effect of excipient composition on the biocompatibility of bupivacaineโ€containing microparticles. Lipidโ€“proteinโ€“sugar particles (LPSPs) composed of 3% (1.3โ€ฮผm diameter) and