ALKALINE PHOSPHATASE ISOENZYME ASSAYS FOR PRENATAL DIAGNOSIS OF CYSTIC FIBROSIS
✍ Scribed by Muller, Françoise; Berg, Sylvie; Frot, Jean-François; Boue, Joëlle; Boue, André
- Book ID
- 122005183
- Publisher
- The Lancet
- Year
- 1984
- Tongue
- English
- Weight
- 147 KB
- Volume
- 323
- Category
- Article
- ISSN
- 0140-6736
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In 36 children with cystic fibrosis (CF) the isoenzymes of alkaline phosphatase (AP) were determined microelectrophoretically in polyacrylamide- and starch-gel. The study was done to evaluate the clinical significance of these additional data for the diagnosis of liver involvement in DF. The results
Activities of the microvillar enzymes gamma-glutamyltranspeptidase (GGTP), aminopeptidase M (APM), phosphodiesterase and maltase have been examined in second-trimester amniotic fluid as possible aids to the early prenatal diagnosis of cystic fibrosis (CF). The two peptidases, GGTP and APM, gave best