Alkaline phosphatase in rodent secondary palate development. A histochemical and biochemical study

✍ Scribed by Sweney, L. R. ;Shapiro, B. L.

• Publisher: John Wiley and Sons
• Year: 1971
• Tongue: English
• Weight: 535 KB
• Volume: 170
• Category: Article
• ISSN: 0003-276X
• DOI: 10.1002/ar.1091700208

✦ Synopsis

Alkaline phosphatase ( AlPase) has been examined histochemically and biochemically in Swiss White (SW ) mouse and Sprague-Dawley (SD) rat embryos during comparable stages of secondary palatal development. In the rats, AlPase was not detectable histochemically until after shelf transposition.

Enzyme activity by biochemical assay was lalw in stages before shelf elevation. The mice, in contrast, showed AlPase in posterior areas of the developing shelves soon after shelf formation by histochemical techniques. With biochemical assays AlPase was higher in mouse than in rat shelvles in early stages. After shelf transposition AlPase activityFin the rat approached AlPase activity in the mouse by biochemical assays, but was demonstrable only in the posterior areas of the secondary palate by histochemical techniques.