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Aldosterone-induced abnormal regulation of ENaC and SGK1 in Dahl salt-sensitive rat

✍ Scribed by Wataru Aoi; Naomi Niisato; Yukinori Sawabe; Hiroaki Miyazaki; Yoshinori Marunaka


Book ID
116292166
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
145 KB
Volume
341
Category
Article
ISSN
0006-291X

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## Abstract α‐ENaC expression and activity is regulated by a variety of hormones including β‐adrenergic agonists via the second messenger cAMP. We evaluated the early intermediate pathways involved in the up‐regulation of SGK1 by DbcAMP and whether SGK1 is a prerequisite for induction of α‐ENaC exp