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Aldosterone diagnosis in hypertension: Comparative evaluation of radioimmunoassays for urinary aldosterone and 18-OH-corticosterone

โœ Scribed by Connolly, T. M. ;Vecsei, P. ;Haack, D. ;Kohl, K. -H. ;Abdelhamid, S. ;Ammenti, A.

Book ID
105211450
Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
889 KB
Volume
56
Category
Article
ISSN
1432-1440

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Monoclonal antibodies specific for 18-hydroxycortisol and their use in an enzyme immunoassay for human urinary 18-hydroxycortisol for diagnosis of primary aldosteronism
โœ Hiroaki Kohno; Seiji Sato; Hitoshi Chiba; Kunihiko Kobayashi; Shigeo Ikegawa; Ta ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 642 KB

We report the development of a monoclonal antibody-based enzyme immunoassay (EIA) specific for human urinary 18hydroxycortisol, a biological marker of primary aldosteronism. Hybrid cell lines (hybridomas) were isolated after fusion between myeloma cells and spleen cells prepared from mice immunized