The physical complications of alcoholism are numerous. 1 ## It is still not clear why some alcoholic patients acquire Different mechanisms are probably involved in different alcocertain organ-specific complications of alcoholism hol-induced end organ diseases, such as those in the liver, whereas
Alcoholism and alcoholic organ damage and genetic polymorphisms of alcohol metabolizing enzymes in Chinese patients
โ Scribed by Y Chao; T Young; H Tang; C Hsu
- Book ID
- 118686540
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 201 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Alcohol dehydrogenase (ADH), aldehyde dehydrogenase (ALDH), and P450IIE1 are the primary enzymes that catalyze the conversion of ethanol to acetaldehyde and then to acetate. Genetic polymorphisms have been reported in ADH2, ADH3, ALDH2, and the 5'-flanking region of P450IIEI. In this study, we used
Liver alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), the principal enzymes responsible for the oxidation of ethanol, are polymorphic at theADH2, ADH3 andALDH2 loci in human beings. Our previous studies have shown that, compared with nonalcoholic individuals, Chinese alcoholic patient