✦ LIBER ✦

Alcoholic liver disease: Natural history

✍ Scribed by Diehl, A M

Publisher: Wiley (John Wiley & Sons)
Year: 1997
Tongue: English
Weight: 109 KB
Volume: 3
Category: Article
ISSN: 1074-3022
DOI: 10.1002/lt.500030303

No coin nor oath required. For personal study only.

✦ Synopsis

A lcohol consumption was identified as a risk factor for liver disease centuries ago when Laennec documented a high prevalence of cirrhosis among heavy drinkers. 1 Modern epidemiological data from many societies confirm a strong correlation between death attributable to cirrhosis and per capita consumption of alcohol. No particular quantity of alcohol consumption predictably results in alcoholic liver disease (ALD). Although evidence suggests that risk increases with habitual alcohol intake of 80 g/d in men and 20 g/d in women, a minority of individuals drinking two to three times these amounts develop significant liver disease. Indeed, only 20% of men drinking the equivalent of two six-packs of beer daily for 10 years become cirrhotic. Hence, most people who drink alcohol do not become cirrhotic, but some people who drink only modestly may develop this lesion.

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