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Alcohol sensitivity related to polymorphism of alcohol-metabolizing enzymes in Japanese

โœ Scribed by Yasuhiko Mizoi; Yoshitsugu Tatsuno; Junko Adachi; Masaaki Kogame; Tatsushige Fukunaga; Satoshi Fujiwara; Shigeru Hishida; Iwao Ijiri

Book ID
113219432
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
531 KB
Volume
18
Category
Article
ISSN
0091-3057

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Polymorphisms in alcohol metabolizing en
Polymorphisms in alcohol metabolizing enzyme genes and alcoholic cirrhosis in Japanese patients: A multivariate analysis
โœ Masayoshi Yamauchi; Yoshihiko Maezawa; Yuji Mizuhara; Mitsuru Ohata; Junichi Hir ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 787 KB

Alcohol dehydrogenase (ADH), aldehyde dehydrogenase (ALDH), and P450IIE1 are the primary enzymes that catalyze the conversion of ethanol to acetaldehyde and then to acetate. Genetic polymorphisms have been reported in ADH2, ADH3, ALDH2, and the 5'-flanking region of P450IIEI. In this study, we used