Hepcidin, the iron hormone, is produced by the liver in response to iron and inflammation. Its synthesis during inflammation is triggered by cytokines, but the details of iron activation are obscure. We tested the role of Kupffer cells and macrophages by studying iron-loaded or inflamed mice with se
β¦ LIBER β¦
Alcohol intake and iron overload: Another role for hepcidin?
β Scribed by Kris V. Kowdley
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 67 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
β¦ Synopsis
Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression.
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