Alcohol consumption and impaired glycoregulation results in a population of 6665 salaried employees
โ Scribed by P. Lombrail; T. Lang; P. Degoulet; F. Aimee; C. Devries; C. Fouriaud; M. C. Jacquinet-Salord
- Book ID
- 104642552
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 494 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0393-2990
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โฆ Synopsis
Alcohol consumption and glycosuria were found to be associated (p less than 0.001) in a population of 6571 salaried employees who underwent a systematic examination. The prevalence of glycosuria was found to range from 1.3% among 2609 non-drinkers to 5% among 816 heavy drinkers (six glasses or more of alcoholic beverage daily). This association was still significant after adjustment for age, sex and body mass index. Similarly, a positive association was observed between fasting glycemia and alcoholic intake in a subgroup of 998 subjects when such a result was available (p less than 0.05).
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Although alcohol intake as well as hepatitis viruses has been associated with hepatocellular carcinoma (HCC), gene-alcohol interactions on HCC risk remain to be elucidated. We conducted a case-control study to examine whether polymorphisms of alcohol dehydrogenase 2 (ADH2) and aldehyde dehydrogenase