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Alcohol and Cigarette Smoking and the Risk of Colorectal Adenomas

✍ Scribed by B. Breuer-Katschinski; K. Nemes; A. Marr; B. Rump; B. Leiendecker; N. Breuer; H. Goebell

Book ID: 110224727
Publisher: Springer US
Year: 2000
Tongue: English
Weight: 65 KB
Volume: 45
Category: Article
ISSN: 0163-2116
DOI: 10.1023/a:1005432804902

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## Abstract Cigarette smoke contains polycyclic hydrocarbons and arylamines that may both be activated by sulfotransferase, encoded by __SULT1A1__. A genetic polymorphism leads to an Arg213His substitution, thereby decreasing enzyme activity and stability and might thus modify the association betwe