Alcohol and aldehyde dehydrogenase genotypes and drinking behavior of Chinese living in Shanghai
โ Scribed by Taro Muramatsu; Wang Zu-Cheng; Fang Yi-Ru; Hu Kou-Bao; Yan Heqin; Koichi Yamada; Susumu Higuchi; Shoji Harada; Hiroaki Kono
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 330 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Liver alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), the principal enzymes responsible for the oxidation of ethanol, are polymorphic at theADH2, ADH3 andALDH2 loci in human beings. Our previous studies have shown that, compared with nonalcoholic individuals, Chinese alcoholic patient
In this study we have examined the roles of alcohol dehydrogenase, aldehyde oxidase, and aldehyde dehydrogenase in the adaptation of Drosophila melanogaster to alcohol environments. Fifteen strains were characterized for genetic variation at the above loci by protein electrophoresis. Levels of in vi
In this study, 1,000 Japanese male alcoholics were consecutively screened by upper gastrointestinal endoscopy with esophageal iodine staining. Associations among cancer-detection rates, drinking and smoking habits, and aldehyde dehydrogenase-2 (ALDH2) genotypes were evaluated. A total of 53 patients
The gene frequencies of ADH2(2) and ALDH2(2) were lower in Tibetan and Mongolian populations than in Vietnamese, Han Chinese, and three Chinese minority populations.
Two types of factors can theoretically modulate alcohol metabolism toward increased acetaldehyde production. These factors are the following: (a) individual, genetically determined isoenzymes with distinct catalytic properties, and (b) modifications of enzyme activity induced by alcohol itself or li