## Abstract In our previous study, we found that polymorphisms of alcohol and aldehyde dehydrogenase (__ADH1B__ and __ALDH2__) are important risks for esophageal squamous cell carcinoma in a Taiwanese population. In this study, we increased the sample size to investigate the modifying effect of lif
Alcohol and Aldehyde Dehydrogenase Gene Polymorphisms Influence Susceptibility to Esophageal Cancer in Japanese Alcoholics
β Scribed by Akira Yokoyama; Taro Muramatsu; Tai Omori; Sachio Matsushita; Haruko Yoshimizu; Susumu Higuchi; Tetsuji Yokoyama; Katsuya Maruyama; Hiromasa Ishii
- Book ID
- 109121292
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 712 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0145-6008
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π SIMILAR VOLUMES
Liver alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), the principal enzymes responsible for the oxidation of ethanol, are polymorphic at theADH2, ADH3 andALDH2 loci in human beings. Our previous studies have shown that, compared with nonalcoholic individuals, Chinese alcoholic patient
## Abstract ## BACKGROUND. It is believed that acetaldehyde plays an important role in alcoholβrelated carcinogenesis; although current epidemiologic studies have provided inconsistent findings on the association between alcohol consumption and the risk of lung cancer. ## METHODS. To clarify the