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Akt up- and down-regulation in response to endoplasmic reticulum stress

โœ Scribed by Toru Hosoi; Kanae Hyoda; Yasunobu Okuma; Yasuyuki Nomura; Koichiro Ozawa


Book ID
113502733
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
463 KB
Volume
1152
Category
Article
ISSN
0006-8993

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The up-regulation of protein phosphatase 2 A (PP2A) is an important factor leading to an inhibition of IFNโฃ signaling caused by viral protein expression. Here, we describe the molecular mechanism involved in PP2Ac up-regulation by HCV and HBV. HCV and HBV protein expression in cells induces an ER st