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AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer

✍ Scribed by Yuanzi Yu; Dongtao Yin; Mohammad O. Hoque; Baoping Cao; Yan Jia; Yunsheng Yang; Mingzhou Guo


Book ID
107694023
Publisher
S. Karger AG
Year
2011
Tongue
English
Weight
397 KB
Volume
33
Category
Article
ISSN
1010-4283

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## Abstract __TMS1__ (target of methylation‐induced silencing) is a CpG island‐associated gene that functions in the regulation of apoptosis and encodes a caspase recruitment domain, a recently described motif found in apoptotic signaling molecules. Recent evidence suggests that silencing of genes