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AKT as locus of cancer positive feedback loops and extreme robustness

โœ Scribed by Radisavljevic, Ziv


Book ID
118762696
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
73 KB
Volume
228
Category
Article
ISSN
0021-9541

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AKT as locus of fragility in robust canc
โœ Ziv Radisavljevic ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 96 KB

## Abstract Metastatic cancer is a complex positive feedback loop system. Such as system has a tendency to acquire extreme robustness. Signaling pathways controlling that robustness can fail completely if an essential element from the signaling is removed. That element is a locus of fragility. Targ