𝔖 Bobbio Scriptorium
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AKT and Oxidative Stress Team Up to Kill Cancer Cells

✍ Scribed by Ignacio Dolado; Angel R. Nebreda


Book ID
113523848
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
360 KB
Volume
14
Category
Article
ISSN
1535-6108

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## Abstract The switch from oxidative phosphorylation to glycolytic metabolism results in cells that generate fewer reactive oxygen species (ROS) and are resistant to the intrinsic induction of apoptosis. As a consequence, glycolytic cancer cells are resistant to radiation and chemotherapeutic agen