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Aklanonic acid-producing mutants of Streptomyces galilaeus and Streptomyces peucetius var. caesius

✍ Scribed by Dr. B. Schlegel; C. Stengel; G. Schumann; H. Prauser; K. Eckardt

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 331 KB
Volume: 27
Category: Article
ISSN: 0233-111X
DOI: 10.1002/jobm.3620270212

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✦ Synopsis

A number of blocked mutants was investigated which were obtained from taxonomically identified h'treptomyces strains producing anthracyclines. Two of these mutants, NTG 061 derived from l ) S . peucetius GREIN, SPALLA, DI MARCO and CANEVAZZI 1963 has been validly published according to Approved Lists of Bacterial Names 1980. The variety, respectively subspecies caesius CASSINELLI, G. et al. 1979, however, has not yet been validated.

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Biotransformation of aklanonic acid by b

Biotransformation of aklanonic acid by blocked mutants of anthracycline-producing strains of Streptomyces galilaeus and Streptomyces peucetius

✍ G. Schumann; C. Stengel; Dr. K. Eckardt; W. Ihn 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 543 KB

Aklanonic acid is an anthracyclinone-related pigment that was found to be an intermediate a t an early stage of the biosynthesis of daunomycinone glycosides by Streptomyces griseus. We now isolated anthracycline-negative mutants of other Streptomyces species and used them in feeding experiments with