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Air to Muscle and Blood/Plasma to Muscle Distribution of Volatile Organic Compounds and Drugs: Linear Free Energy Analyses

✍ Scribed by Abraham, Michael H.; Ibrahim, Adam; Acree, William E.

Book ID: 124078177
Publisher: American Chemical Society
Year: 2006
Tongue: English
Weight: 57 KB
Volume: 19
Category: Article
ISSN: 0893-228X
DOI: 10.1021/tx050337k

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Literature values of the in vivo distribution (BB) of drugs from blood, plasma, or serum to rat brain have been assembled for 207 compounds (233 data points). We find that data on in vivo distribution from blood, plasma, and serum to rat brain can all be combined. Application of our general linear f