𝔖 Bobbio Scriptorium
✦   LIBER   ✦

aHIF but not HIF-1α transcript is a poor prognostic marker in human breast cancer

✍ Scribed by Anne Cayre, Fabrice Rossignol, Eric Clottes, Frédérique Penault-Llorca

Book ID
120701140
Publisher
BioMed Central
Year
2003
Tongue
English
Weight
732 KB
Volume
5
Category
Article
ISSN
1465-5411

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Hypoxia inducible factor-1α is a prognos
Hypoxia inducible factor-1α is a prognostic marker in premenopausal patients with intermediate to highly differentiated breast cancer but not a predictive marker for tamoxifen response
✍ Åsa Kronblad; Karin Jirström; Lisa Rydén; Bo Nordenskjöld; Göran Landberg 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 765 KB

## Abstract Hypoxia is common in many solid tumours, including breast cancer. Hypoxia triggers the expression of hypoxia inducible factor‐1α (HIF‐1α), and HIF‐1α has been associated with an impaired prognosis in breast cancer and down‐regulation of the oestrogen receptor (ER), potentially affecting

p27Kip1 is a predictive factor for tamox
p27Kip1 is a predictive factor for tamoxifen treatment response but not a prognostic marker in premenopausal breast cancer patients
✍ Maria Stendahl; Sofie Nilsson; Caroline Wigerup; Karin Jirström; Per Ebbe Jönsso 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 489 KB

## Abstract The cell‐cycle regulating protein p27^Kip1^ (p27) has dual roles by acting as both a cdk inhibitor and as an assembly factor for different cdk complexes. Loss of p27 has been linked to malignant features in tumours; however, the exact role of p27 deregulation in breast cancer regarding