Agressive Lymphomas

✍ Scribed by Georg Lenz, Gilles Salles

Publisher: Springer International Publishing
Year: 2019
Tongue: English
Leaves: 357
Series: Hematologic Malignancies
Edition: 1st ed.
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This book summarizes current knowledge of the biology and molecular pathogenesis of aggressive lymphomas and reviews the state of the art in diagnostic and therapeutic strategies. The aim is both to provide the reader with a sound understanding of the very significant progress that has been achieved in the understanding and management of these malignancies over recent years and to facilitate appropriate choice of the therapeutic strategy in individual cases. The assessment of different prognostic parameters are clearly presented in order to permits effective risk stratification that impacts on treatment choice. Recent insights into lymphomagenesis are exemplified and may assist in identifying emerging therapeutic targets. The comprehensive and up-to-date nature of the book will make it an ideal reference for all physicians and researchers interested in lymphoma, including clinicians from various medical specialties, biologists, pathologists, radiologists and nuclear medicine specialist, as well as students.

✦ Table of Contents

Front Matter ....Pages i-vii
Front Matter ....Pages 1-1
Epidemiology of Aggressive Lymphomas (James R. Cerhan)....Pages 3-40
Pathology and Molecular Pathogenesis of DLBCL and Related Entities (Laura Pasqualucci, German Ott)....Pages 41-73
Pathology and Molecular Pathogenesis of Burkitt Lymphoma and Lymphoblastic Lymphoma (Hélène A. Poirel, Maria Raffaella Ambrosio, Pier Paolo Piccaluga, Lorenzo Leoncini)....Pages 75-94
Pathology and Molecular Pathogenesis of T-Cell Lymphoma (Javeed Iqbal, Laurence de Leval)....Pages 95-141
Front Matter ....Pages 143-143
Standard of Care in First-Line Therapy of DLBCL (Greg Nowakowski, Fabian Frontzek, Norbert Schmitz)....Pages 145-155
Standard of Care Relapsed DLBCL (Kayane Mheidly, Roch Houot, Michael Scordo, Craig Moskowitz)....Pages 157-166
Burkitt Lymphoma (Kieron Dunleavy, Martine Chamuleau)....Pages 167-175
Human Immunodeficiency Virus-Related Lymphomas (Josep-Maria Ribera, Richard F. Little)....Pages 177-188
Primary CNS Lymphoma (Agnieszka Korfel)....Pages 189-199
Extranodal Localization of Aggressive Lymphoma (Jeremy S. Abramson, Armando López-Guillermo)....Pages 201-212
CD20-Negative Aggressive Lymphomas (Jorge J. Castillo)....Pages 213-226
Standard of Care in T-Cell Lymphoma (Alessandro Broccoli, Dai Chihara, Michelle A. Fanale, Pier Luigi Zinzani)....Pages 227-244
Aggressive Lymphoma in Children and Adolescents (Birte Wistinghausen, Birgit Burkhardt)....Pages 245-282
Front Matter ....Pages 283-283
Role of Modern Imaging with FDG-PET/CT in Aggressive Lymphoma (Judith Trotman, Michel Meignan)....Pages 285-295
Kinase Inhibitors in Large Cell Lymphoma (Franck Morschhauser, Salomon Manier, Nathan Fowler)....Pages 297-305
Immunological Approaches (Guillaume Cartron, F. Frontzek, N. Schmitz)....Pages 307-324
Therapeutic Modulators of Apoptosis and Epigenetics in Aggressive Lymphoma (Michael J. Dickinson, John F. Seymour)....Pages 325-341
Targeted Therapeutics for Lymphoma: Using Biology to Inform Treatment (T. E. C. Cummin, M. S. Cragg, J. W. Friedberg, P. W. M. Johnson)....Pages 343-360

✦ Subjects

Medicine & Public Health; Hematology; Pathology; Immunology

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