Agonistic Properties of Cannabidiol at 5-HT1a Receptors
โ Scribed by Ethan B. Russo; Andrea Burnett; Brian Hall; Keith K. Parker
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 199 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0364-3190
No coin nor oath required. For personal study only.
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Syntheses of carbon-14 labelled versions of indolic 5HT1 agonists sumatriptan (GR43175) ( 1 ) , GR40370 (2a) and naratriptan (GR85548) (3a) are described. Introduction of the label via cyanation of ketoforrnanilides, formed by oxidative cleavage of an indole ring, ensured incorporation of carbon-14