The key immunological event in the pathogenesis of the autoimmune liver disease primary biliary cirrhosis is breakdown of T-cell self-tolerance to pyruvate dehydrogenase complex (PDC). The mechanism resulting in this breakdown of tolerance remains unclear. Mice exposed to self-PDC mount no immune re
Agonistic antibodies to Fas induce a breach in the endothelial lining of the liver and a breakdown in B cell tolerance
β Scribed by M. M. Newkirk; U. Nowak; E. Skamene; D. Iera; J. Desbarats
- Book ID
- 108699524
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 195 KB
- Volume
- 147
- Category
- Article
- ISSN
- 0009-9104
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