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Agonist-specific reverse regulation of muscarinic receptors by transition metal ions and guanine nucleotides

✍ Scribed by David Gurwitz; Mordechai Sokolovsky


Book ID
118314304
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
509 KB
Volume
96
Category
Article
ISSN
0006-291X

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## Abstract The regulation of muscarinic receptor binding by guanine nucleotides and N‐ethylmaleimide (NEM) was investigated using the agonist ligand, [^3^H] cis methyldioxolane ([^3^H] CD). Characterization studies on rat forebrain homogenates showed that [^3^H] CD binding was linear with tissue c