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Agonist-induced phosphorylation and desensitization of the P2Y2nucleotide receptor

✍ Scribed by Rosa V. Flores; Melvin G. Hernández-Pérez; Edna Aquino; Richard C. Garrad; Gary A. Weisman; Fernando A. Gonzalez


Book ID
106457673
Publisher
Springer
Year
2005
Tongue
English
Weight
749 KB
Volume
280
Category
Article
ISSN
0300-8177

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## Abstract Activation of P2Y~2~ receptors by extracellular nucleotides has been shown to induce phenotypic differentiation of human promonocytic U937 cells that is associated with the inflammatory response. The P2Y~2~ receptor agonist, UTP, induced the phosphorylation of the MAP kinases MEK1/2 and