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Agonist-independent modulation of N-type calcium channels by ORL1 receptors

✍ Scribed by Beedle, Aaron M; McRory, John E; Poirot, Olivier; Doering, Clinton J; Altier, Christophe; Barrere, Christian; Hamid, Jawed; Nargeot, Joel; Bourinet, Emmanuel; Zamponi, Gerald W

Book ID
109940342
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
836 KB
Volume
7
Category
Article
ISSN
1097-6256

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## Abstract Opioids modulate the electrical activity of magnocellular neurons (MCN) and inhibit neuropeptide release at their terminals in the neurohypophysis. We have previously shown that µ‐opioid receptor (MOR) activation induces a stronger inhibition of oxytocin (OT) than vasopressin (AVP) rele