Peripheral cytopenias are common in patients with agnogenic myeloid metaplasia (AMM). They are an important cause of morbidity and mortality, and their treatment is difficult. We report on 4 patients with AMM and severe cytopenia treated with danazol (400-600 mg/ day). Three of them became independe
Agnogenic myeloid metaplasia associated with Klinefelter syndrome: a case report
β Scribed by S. Kumar; D. Menke; G. Dewald; G. Colon-Otero
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 30 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0939-5555
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π SIMILAR VOLUMES
Klinefelter syndrome increases the risk of developing breast cancer to approximately 1/5 that of women and 20 times that of normal men. A case report and the patient's response to hormone manipulation for metastatic disease is described.
## Background. The interrelation between plasma cell dyscrasia and myelofibrosis or agnogenic myeloid metaplasia (AMM) is unclear. The existence of two distinct syndromes has been proposed: (1) plasma cell dyscrasia associated with simple marrow fibrosis caused by the secretion of lymphokines and
## Abstract An 18βyearβold male with Klinefelter's syndrome presented with a mature teratoma of the mediastinum. He was treated with deβbulking surgery and brief cisplatinβbased chemotherapy. Ten years later, he presented with paraplegia and was found to have an isolated epidural mass. The mass was