Aging and cross-linking of skin collagen
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Mitsuo Yamauchi; David T. Woodley; Gerald L. Mechanic
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Article
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1988
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Elsevier Science
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English
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This report represents a clear demonstration of a cross-link in collagen whose abundance is related to chronological aging of an organism. Recently its structure was identified as histidinohydroxylysinonorleucine. Quantification of the cross-link in various aged samples of bovine and human skin indi