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Aggregation and Porin-like Channel Activity of a β Sheet Peptide

✍ Scribed by Thundimadathil, Jyothi; Roeske, Roger W.; Jiang, Hao-Yuan; Guo, Lili

Book ID
126223633
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
515 KB
Volume
44
Category
Article
ISSN
0006-2960

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Fibril aggregation inhibitory activity o
Fibril aggregation inhibitory activity of the β-sheet breaker peptides: a molecular docking approach
✍ Maria Giovanna Chini; Mario Scrima; Anna Maria D'Ursi; Giuseppe Bifulco 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB

## Abstract In the present study, we used a molecular docking as a rapid, interactive method to study the inhibition of fibrillogenesis process by β‐sheet breaker peptide (BSB) (Ac‐L^1^‐V^2^‐(NMet)F^3^‐F^4^‐A^5^‐NH~2~). Our aim was to find the complex (Aβ:BSB) that blocks the aggregation of the fib