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Aggravation of myocardial dysfunction by injurious mechanical ventilation in LPS-induced pneumonia in rats

✍ Scribed by Smeding, Lonneke ;Kuiper, Jan ;Plötz, Frans B ;Kneyber, Martin CJ ;Groeneveld, AB


Book ID
121621815
Publisher
BMJ
Year
2013
Tongue
English
Weight
418 KB
Volume
14
Category
Article
ISSN
2052-4439

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Postischemic injury in isolated rat hear
✍ Robert J. A. M. Verbunt; Willem G. Dockum; E. M. Lars Bastiaanse; Janneke M. Ega 📂 Article 📅 1996 🏛 Springer 🌐 English ⚖ 602 KB

The aim of this study was to test the hypothesis that a decreased myocardial concentration of reduced glutathione (GSH) during ischemia renders the myocardium more susceptible to injury by reactive oxygen species generated during early reperfusion. To this end, rats were pretreated with L-buthionine