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AGEs Induce Cell Death via Oxidative and Endoplasmic Reticulum Stresses in Both Human SH-SY5Y Neuroblastoma Cells and Rat Cortical Neurons

✍ Scribed by Yin, Qing-Qing; Dong, Chuan-Fang; Dong, Si-Qin; Dong, Xue-Li; Hong, Yan; Hou, Xun-Yao; Luo, Ding-Zhen; Pei, Jin-Jing; Liu, Xue-Ping


Book ID
118059985
Publisher
Springer
Year
2012
Tongue
English
Weight
631 KB
Volume
32
Category
Article
ISSN
0272-4340

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## Abstract Free cytoplasmic dopamine may be involved in the genesis of neuronal degeneration in Parkinson's disease and other such diseases. We used SH‐SY5Y human neuroblastoma cells to study the effect of dopamine on cell death, activation of stress‐induced pathways, and expression of α‐synuclein