✦ LIBER ✦

Ageing-related decline in adenosine A1 receptor binding in the rat brain: An autoradiographic study

✍ Scribed by Peter Meerlo; Viktor Roman; Eszter Farkas; Jan N. Keijser; Csaba Nyakas; Paul G.M. Luiten

Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 25 KB
Volume: 79
Category: Article
ISSN: 0360-4012
DOI: 10.1002/jnr.20427

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Ageing-related decline in adenosine A1 r

✍ Peter Meerlo; Viktor Roman; Eszter Farkas; Jan N. Keijser; Csaba Nyakas; Paul G. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 194 KB

## Abstract The adenosine system has important neuromodulatory and neuroprotective functions in the brain. Several lines of evidence suggest that ageing is associated with major alterations in the adenosine system, which may be partially responsible for changes in sleep, mood, and cognition. In the

Age-dependent changes in adenosine A1 re

Age-dependent changes in adenosine A1 receptor and uptake site binding in the mouse brain: An autoradiographic study

✍ Antigoni Ekonomou; Olga Pagonopoulou; Fevronia Angelatou 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 284 KB 👁 3 views

Ageing is a multifactorial, inevitable event of life span, which affects neurotransmission in the CNS. Since adenosine is a major neuromodulator of the synaptic activity, it was of interest to investigate the possible modification of the adenosinergic system in the brain during ageing. Using "in vit

Age-dependent decline of dopamine D1 rec

Age-dependent decline of dopamine D1 receptors in human brain: A PET study

✍ Yue Wang; Grace L.Y. Chan; James E. Holden; Teresa Dobko; Edwin Mak; Michael Sch 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 86 KB

Radioligand binding studies in animals have demonstrated age-related loss of dopamine receptors in the caudate and putamen. In humans, while age-related declines in dopamine D2 receptors have been consistently reported, the effects of ageing on D1 receptors have been controversial. We used positron

Modulation of endogenous GABA release by

Modulation of endogenous GABA release by an antagonistic adenosine A1 / dopamine D1 receptor interaction in rat brain limbic regions but not basal ganglia

✍ R. Dayne Mayfield; Brice A. Jones; Heather A. Miller; Johanna K. Simosky; Gaynor 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 123 KB 👁 2 views

Behavioral and biochemical studies suggest that a negative interaction exists between adenosine A 1 and dopamine D 1 receptors in the brain and that this may contribute to the psychomotor effects of adenosine receptor agonists and antagonists. We examined the functional significance of A 1 and D 1 r

Effects of chronic 17β-estradiol treatme

Effects of chronic 17β-estradiol treatment on the serotonin 5-HT1A receptor mRNA and binding levels in the rat brain

✍ Marie K. Österlund; Christer Halldin; Yasmin L. Hurd 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 117 KB 👁 1 views

Acute 17␤-estradiol treatment had been shown to downregulate the 5-HT 1A receptor mRNA expression in limbic areas of the female rat brain. The aim of the present study was to determine the effects of chronic 17␤-estradiol treatment on 5-HT 1A receptor mRNA expression and 5-HT 1A receptor binding in

Widely expressed transcripts for chemoki

Widely expressed transcripts for chemokine receptor CXCR1 in identified glutamatergic, γ-aminobutyric acidergic, and cholinergic neurons and astrocytes of the rat brain: A single-cell reverse transcription-multiplex polymerase chain reaction study

✍ M. Danik; C. Puma; R. Quirion; S. Williams 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 230 KB

## Abstract Increasing evidence suggests that the chemokine interleukin (IL)‐8/CXCL8 plays important roles in CNS development, neuronal survival, modulation of excitability, and neuroimmune response. Recently, we have shown that CXCL8 can acutely modulate ion channel activity in septal neurons expr