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Ageing of fixed cytological preparations produces degradation of chromosomal DNA

โœ Scribed by Mezzanotte, R.; Vanni, R.; Flore, O.; Ferrucci, L.; Sumner, A.T.


Book ID
120601328
Publisher
S. Karger AG
Year
1988
Tongue
French
Weight
736 KB
Volume
48
Category
Article
ISSN
1424-8581

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The DNA fragments produced by AluI and B
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AluI and BstNI restriction endonucleases were used to study cytological and biochemical effects on centromere DNA in fixed mouse chromosomes. These enzymes were employed, as it is known that AluI is incapable of attacking major satellite DNA, contrary to BstNI that is known to cut this DNA fraction