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Ageing increases vulnerability to Aβ42 toxicity in drosophila

✍ Scribed by Fiona Kerr; Iain Rogers; Pedro Martinez; John Hardy; Simon Lovestone; Linda Partridge

Book ID
118468497
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
57 KB
Volume
8
Category
Article
ISSN
1552-5260

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## Abstract Astrocytosis is a common feature of amyloid plaques, the hallmark of Alzheimer's disease (AD), along with activated microglia, neurofibrillary tangles, and β‐amyloid (βA) deposition. However, the relationship between astrocytosis and neurodegeneration remains unclear. To assess whether