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Aged murine killer T-cell clones acquire specific cytotoxicity for P815 mastocytoma cells

✍ Scribed by Simon, M. M.; Weltzien, H. U.; Bühring, H. J.; Eichmann, K.


Book ID
109734914
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
374 KB
Volume
308
Category
Article
ISSN
0028-0836

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We have investigated the effect of pre-treatment with the anti-cancer drugs cisplatin and etoposide on the susceptibility of P815 murine mastocytoma cells to lysis by murine spleen-derived anti-CD3-activated killer-T (AK-T) cells. A 20 hr pre-treatment with cisplatin (0.2-2 microg/ml) or etoposide (