✦ LIBER ✦

Age-related increase of CD45RO+ lymphocytes in physically active adults

✍ Scribed by Holger Gabriel; Barbara Schmitt; Wilfried Kindermann

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 232 KB
Volume: 23
Category: Article
ISSN: 0014-2980
DOI: 10.1002/eji.1830231049

No coin nor oath required. For personal study only.

✦ Synopsis

The CD45RO phenotype of peripheral blood CD4+ and CD8+ lymphocytes were determined in physically active males ( n = 171) and females ( n = 70) ranging in age from 15-68 years. Direct immunofluorescence and dual color flow cytometry was performed for analysis. Absolute cell numbers (r = 0.473) and percentages of CD4+ CD45RO+ (r = 0.648) within the CD4+ population, percentage of CD8+ CD45RO+ cells within the CD8+ lymphocytes (I-= 0.498) and total lymphocyte number (r = -0.242) correlated significantly (p € 0.001) with age. We conclude that the age-related increase of CD45RO+ T cells indicates a gradual increase of activated T cells.

📜 SIMILAR VOLUMES

Increase of atypical lymphocytes express

Increase of atypical lymphocytes expressing CD4+/CD45RO+ in an infectious mononucleosis-like syndrome associated with hepatitis A virus infection

✍ Hidehiro Watanabe; Hideaki Sekine; Tomonori Uruma; Sai Nagasaki; Tokuroh Tsunoda 📂 Article 📅 2009 🏛 Springer 🌐 English ⚖ 285 KB

Selective loss of peripheral blood CD45R

Selective loss of peripheral blood CD45RO+T lymphocytes correlates with increased levels of serum cytokines and endothelial cell-derived soluble cell adhesion molecules in patients with chronic idiopathic neutropenia of adults

✍ H. A. Papadaki; G. D. Eliopoulos 📂 Article 📅 1998 🏛 Springer 🌐 English ⚖ 354 KB

Functional importance of CD4+ and CD8+ c

Functional importance of CD4+ and CD8+ cells in cytotoxic lymphocytes activity and associated gene expression. Impact on the age-related decline in lytic activity

✍ Eda T. Bloom 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 527 KB