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Age-related Epstein–Barr virus-associated B-cell lymphoproliferative disorders in elderly White patients

✍ Scribed by Stanislas Nimubona; Marc Bernard; Sophie De Guibert; Hélène Duval; Sylvie Caulet-Maugendre; Patrick Tass; Thierry Lamy


Book ID
108780920
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
979 KB
Volume
57
Category
Article
ISSN
0309-0167

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EBV infects B lymphocytes in vivo and establishes a life-long persistent infection in the host. The latent infection is controlled by EBV-specific MHC class 1-restricted CTL. Immunosuppression reduces CTL activity, and this facilitates outgrowth of EBV+ve B cell lymphoproliferative disease (BLPD). B