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Age-related dopamine D2/D3 receptor loss in extrastriatal regions of the human brain

✍ Scribed by Valtteri Kaasinen; Harry Vilkman; Jarmo Hietala; Kjell Någren; Hans Helenius; Hans Olsson; Lars Farde; Juha O. Rinne

Book ID
117411081
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
204 KB
Volume
21
Category
Article
ISSN
0197-4580

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✍ Lars H. Pinborg; Charlotte Videbæk; Gitte M. Knudsen; Carl-Gunnar Swahn; Christe 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB

The iodinated benzamide epidepride, which shows a picomolar affinity binding to dopamine D(2) receptors, has been designed for in vivo studies using SPECT. The aim of the present study was to apply a steady-state condition by the bolus/infusion approach with [(123)I]epidepride for the quantification