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Age-related disease penetrance in a large medullary thyroid cancer family with a codon 609 RET gene mutation

✍ Scribed by HALLING, K; BUFILL, J; COTTER, M; ARTZ, S; CARPENTER, A; SCHAID, D; HARTMANADAMS, H; CHANG, H; BOUSTANY, M; FITHIAN, L


Book ID
122709010
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
1997
Tongue
English
Weight
787 KB
Volume
2
Category
Article
ISSN
1532-8619

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The multiple endocrine neoplasia type 2 (MEN2) syndromes and Hirschsprung's disease (HSCR) are inherited neurocristopathies characterized by medullary thyroid carcinoma (MTC), pheochromocytoma, parathyroid disease, and gastrointestinal neuromatosis. Mutations in the RET proto-oncogene are the underl